Category: Neuroradiology, Region: Head-Temporal bones, Plane: Other
(a) low power view of the tumour area showing sheets and fascicles of spindle-shaped cells (H&E ; X40 magnification). (b) the edge of the tumour is ill defined ; the cells are seen to infiltrate the adjacent adipose tissue and skeletal muscle bundles (arrows) (H&E ; X40 magnification). (c) focal whorl formation (arrows) is seen, mitosis is low (1 per 10 high power fields), necrosis is not seen (H&E ; X200 magnification). (d) immunohistochemistry shows patchy epithelial membrane antigen (EMA) positivity (picture). The cells are also positive for vimentin and S100, but are negative for CD-34, melan-A, HMB-45, SMA and desmin.