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Unique! - Interactive Radiology teaching files

Diagnosis: Subarachnoid hemorrhage, subdural bleed, brain edema, cerebral vasospasm
Noncontrast head CT :: Axial images of a CTA of the brain :
MIP images of a CTA of the brain :: Volume rendered images of a CTA of the brain :

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Dare To Share! Radiology case and image exchange

A new program was launched on Radiolopolis: "Dare To Share!". Dare To Share! is a project, which allows sharing cases between researchers and colleagues. Users may find interesting or needed cases/images for different kind of projects (studies, books, publications, presentations etc.) while assuring the owner's credentials/copyright of the case. Direct contact between the searcher and the owner of the case provides also a good opportunity to get to know new, potential partners for future projects. More infos about the Dare To Share! program can be found here.




Latest Radiology News



Get more news and latest publications
Scintigraphy for Evaluation of Patients for GI Motility Disorders—The Referring Physician's Perspective
This article discusses a physician's perspective on evaluating GI transit in patients with suspected GI disorders, particularly those involving the stomach for gastroparesis and the colon in patients with constipation.
(Source: Seminars in Nuclear Medicine)

Update on Gastrointestinal Radiopharmaceuticals and Dosimetry Estimates
The gold standard technique for measuring gastric emptying is scintigraphy using radiolabeled test meals. Recently, a standardized radiolabeled solid meal has been proposed and adopted by many centers. There is still a need for alternative meals, and several such meals with demonstrated radiolabel stability have been evaluated in small numbers of subjects. Updated radiation dosimetry associated with these meals has been calculated for adult males and adult females with normal gastrointestinal transit as well as transit abnormalities.
(Source: Seminars in Nuclear Medicine)

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Liver Function Testing with Nuclear Medicine Techniques Is Coming of Age
This article reviews current knowledge on liver function studies and focuses on those nuclear medicine tests available to study the whole liver and regional liver function. The clinical application driving these tests, prediction of remnant liver function after partial hepatectomy for primary liver malignancy or metastatic disease, is addressed here in detail. The test was recently validated for this specific application and was shown to be better than the current standard of practice (computed tomography volumetry), particularly in patients with hepatic comorbidities like cirrhosis, steatosis, or cholestasis. Furthermore, early assessment of regional liver function increase after preoperative portal vein embolization becomes possible with this technology. The limiting factor to a wider ac...

Letter from the Editors: Functional Studies of the Gastrointestinal Tract
As pointed out by Dr. Alan Maurer in his guest editorial, it has been more than 15 years since he guest edited another Seminars issue, a two-part review of gastrointestinal (GI) nuclear imaging. A significant portion of the progress that has been made relates to attempted standardization of several of these studies. In particular, cooperative efforts between GI, radiology, and nuclear medicine societies have resulted in standardized methodology for gastric emptying studies. Whereas, half-time of emptying (T1/2) was previously considered the accepted key value or “gold standard,” current thoughts center more on the retention values at specific time intervals; particularly four hours post-ingestion of a labeled solid egg meal. Additionally, several alternative test meals yielding similar...

Methods for the Assessment of Small-Bowel and Colonic Transit
Transit assessment of the small intestine and colon is relevant in the study of physiology, pathophysiology, and pharmacodynamics, and there is increasing use of small-bowel and colonic transit measurements in clinical practice as well. The main methods that are applied in clinical practice are substrate-hydrogen breath tests for small-bowel transit and radiopaque markers for colonic transit. Over the past 2-3 decades, scintigraphy has become the preferred standard in research studies, particularly for studies of pathophysiology and pharmacodynamics. New approaches include experimental stable isotope measurement of orocecal transit and the recently approved method using a wireless motility capsule that is validated as an accurate measurement of small-bowel and colonic transit.
(Source: Sem...

Sincalide Cholescintigraphy—32 Years Later: Evidence-Based Data on Its Clinical Utility and Infusion Methodology
Sincalide cholescintigraphy was first reported to have clinical utility in 1980. Since then, many publications have found that a reduced gallbladder ejection fraction (GBEF) can confirm the clinical diagnosis of acalculous chronic gallbladder disease and predict symptomatic relief with cholecystectomy. However, some publications had not found the test clinically predictive. Many different sincalide infusion methods and normal values have been used. It had been suspected that the different infusion methods and normal values might account for the variability in reported utility. Furthermore, clinical review articles have raised questions about the evidence-based quality of the published data on the diagnostic utility of sincalide cholescintigraphy. A recently published multicenter trial has ...

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Advancing Gastric Emptying Studies: Standardization and New Parameters to Assess Gastric Motility and Function
For many years, gastric emptying (GE) studies were performed using various local protocols and different radiolabeled meals. This lack of standardization and normal values made the test results unreliable and difficult to compare from one site to another. A recent consensus has been published that now provides guidance and standardization on how to perform a radiolabeled solid-meal GE study. It is widely recognized, however, that simple measurement of total GE of a solid meal often does not provide an answer to the etiology of symptoms for a large number of patients who present with functional dyspepsia. Advances in our understanding of the different roles of the fundus and antrum and their complex interaction with the proximal small bowel and central nervous system have led to the develop...

Guest Editorial: Gastrointestinal Nuclear Medicine: Are We Making Progress?
In my last guest editorial on gastrointestinal (GI) nuclear medicine in the Seminars in Nuclear Medicine in October 1995, I pointed out that there are few, if any, other nuclear medicine studies, such as gastric emptying, that are considered a gold standard with which other methods need to be compared. I stressed, however, that there was the need for continued efforts within the nuclear medicine community to prevent tarnishing this gold standard. Since then, we have made significant progress especially in standardizing gastric emptying. Additional progress, however, still needs to be made to prevent new imaging and nonimaging technologies from replacing scintigraphy as the primary modality for assessing gastric emptying. In this edition of Seminars, I have brought together several leaders ...

Hepatobiliary Scintigraphy in Acute Cholecystitis
Hepatobiliary scintigraphy is a mature imaging technique for evaluation of patients with acute cholecystitis (AC). It is effective in calculous and acalculous forms of AC. The test is used in contemporary medical practice as the arbiter when the findings from screening abdominal ultrasound do not fit a clinical picture. It is also performed in severely ill patients who have AC suspected on other testing, but whose frail condition and high operative risk demand the highest level of certainty. This review, therefore, examines all technique variations of hepatobiliary scintigraphy, offering an approach that may best fit a variety of clinical situations and philosophies on AC.
(Source: Seminars in Nuclear Medicine)

Blood metabolite data in response to maximal exercise in healthy subjects
SummaryMaximal exercise test with gas exchange measurement evaluates exercise capacities with maximal oxygen uptake (VO2max) measurement. Measurements of lactate (L), lactate/pyruvate ratio (L/P) and ammonium (A) during rest, exercise and recovery enhance interpretative power of maximal exercise by incorporating muscular metabolism exploration. Maximal exercise test with gas exchange measurement is standardized in cardiopulmonary evaluations but, no reference data of blood muscular metabolites are available to evaluate the muscular metabolism. We determined normal values of L, L/P and A during a standardized maximal exercise and recovery in 48 healthy sedentary volunteers and compared with results obtained in four patients with exercise intolerance and a mitochondrial disease. In healthy s...


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